Sunday, February 23, 2020

I am not sure ( just follow the guideline ) Essay

I am not sure ( just follow the guideline ) - Essay Example Ultimately, a new double helix structure consisting of the old and new daughter strand develops (Mott & Berger, 2007). The formation of the replication fork is necessary for DNA replication. The replication fork is the structure formed when a DNA double helix opens up to facilitate this process. Replication starts at sites referred to as origins of replication where nucleotides are attached to the newly growing strand. It is noteworthy that DNA replication occurs in both directions of the bubble; hence, making the replication process fast (Mott & Berger, 2007). The initiation phase is the first stage of DNA replication. During this state, the DNA double helix structure unwinds to expose each complementary strand. Specialized enzymes and protein complexes act in combination, to facilitate the process. At first, helicases are used to unwind the double helix structure. After the unwinding process, protein complexes attach to each strand for the incorporation of new nucleotide bases. DNA polymerase is responsible for the biosynthesis of new strands (Mott & Berger, 2007). The elongation phase is the next step after the initiation phase. During this stage, new daughter strands are copied from the template strand and the process is facilitated by the replication mechanism. The enzyme DNA polymerase is responsible for this elongation process of progressing along the template strand, as new nucleotide bases join up to form new daughter strands. It is noteworthy that DNA replication takes place in the 5’ to 3’ direction. The synthesis of new daughter strands requires an RNA primer, which is synthesized by the primase enzyme. The primer has a 3’ end where the first nucleotide is added with the aid of DNA polymerase. Ultimately, the RNA primer is replaced by DNA molecules when synthesis of the daughter strand is complete (Parkhomchuk et al.,

Friday, February 7, 2020

Auditing Case Study Example | Topics and Well Written Essays - 1500 words

Auditing - Case Study Example Due to reluctance of tone of Societe Generale, the company had to face a loss of almost $7.2 billion in 2008. It is in this context that Societe Generale provided higher concentration on the front office activities and there was less consideration towards back office performances. As a consequence, there was imbalance between the control of front office and back office functions (Beasley, M. S. & Et. Al., â€Å"How a Low Risk Trading Caused a $7.2 billion Loss†). Due to this reason, Societe Generale was incompetent to develop acute inspections essential for controlling the roles and responsibilities of employees. From the case study, it can be observed that like other organizations, Societe Generale had also become quite determined about drumming up its market worth. Thus, it did not provide much attention towards the traders and its responsibilities for managing the risks, while it rendered high significance for financial organizations in order to maintain profitability (Wart zman, â€Å"Executives Are Wrong to Devalue Values†). According to Canadian Auditing Standard (CAS), ‘Tone at the Top’ outlines the principles of a business unit and administration’s obligation to aptitude and beliefs (Hartley, â€Å"Tips for Cost-Effective CAS Application†). Tone at the top is necessary for better financial control in any organization. By judging the tone at the top of Societe Generale it can be characterized that it had certain lacunas of internal control which can be categorized as the reason for huge loss faced by the company. For any organization, the top level administration must be clear regarding the rules of business because different organizations have different risk desires. In Societe Generale the management was unable to apply the rules of business throughout the internal working culture. There is need for better internal management which can scrutinize the activities of all employees so that any kind of illegal activit ies can be detected and prevented accordingly (Beasley, M. S. & Et. Al., â€Å"How a Low Risk Trading Caused a $7.2 billion Loss†). Question 3 CAS describes that maltreatments in the financial statements ascend from either fraudulent activities or accidental mistakes (OAS, â€Å"Canadian Auditing Standards†). Fraudulent activity comprises three aspects which are pressures or incentives, opportunity and rationalization. Pressure or incentive is the aspect which influences or tends to give reasons to an individual to conduct fraud. With respect to Jerome Kerviel (one of the traders of Societe Generale), as a trader, the earning of Kerviel was quite low in comparison with other top level traders. He even did not consider himself as a trader due to his low earnings. Thus, his incentive for conducting fraudulent activity was to enhance his reputation within the company and thus increase the bonus amount (Beasley, M. S. & Et. Al., â€Å"How a Low Risk Trading Caused a $7.2 billion Loss†). Hence, he was constrained for gaining more money by undertaking monetary risks. Rationalization is the other aspect in majority of fraud cases. It involves reconciling the behavior of the individual alleged for committing fraudulent activities. After disclosure of the fraudulent activity of Kerviel, his rationalization was to make sure that his superiors were aware regarding his activities. Kerviel had articulated that his superiors